Heart & Vascular Center

Phone Numbers

Lexington Medical Heart and Vascular Center

Cardiology
(803) 744-4900
Cardiothoracic Surgery
(803) 936-3275
Vascular Surgery
(803) 936-7095

Cardiac Rehabilitation

Main Campus
(803) 791-2621
LMC Lexington
(803) 358-6180
LMC Irmo
(803) 732-5388

Research Trials

Ongoing Clinical Trials

  • Access to new treatments before they become available to everyone
  • Driving innovation in research

"These were the best professionals I’ve ever seen. They were amazing."

— Lewis, Heart & Vascular Center Patient

Research Trials

We offer qualifying patients access to the latest clinical trials.

PEERLESS Study

Description
The primary study objective is to compare the clinical outcomes of patients treated with the Flow Triever System versus Catheter-Directed Thrombolysis (CDT) for use in the treatment of acute intermediate-high-risk pulmonary embolism (PE).

Open to enrollment.

Posted By: Dr. Robert Leonardi

Posted Date: 4/18/2022

Location: Heart and Vascular Center

ACURATE IDE

Description
ACURATE IDE: Transcatheter Replacement of Stenotic Aortic Valve through Implantation of ACURATE in Subjects indicated for TAVR.

The purpose of this study is to evaluate the safety and effectiveness of the ACURATE Transfemoral Aortic Valve System for transcathereter aortic valve replacement (TAVR) in patients with severe native aortic stenosis who are indicated for TAVR.

Open to enrollment.

Posted By: Dr. Robert Leonardi

Posted Date: 3/25/2022

Location: Heart and Vascular Center

Champion AF (OTE)

Description
WATCHMAN FLX versus NOAC for Embolic Protection in the management of patients with Non-Valvular Atrial Fibrillation.

 To prevent stroke in patients with atrial fibrillation is long-term oral anticoagulation (OAC) therapy (blood thinner medication) or, in appropriately selected patients, implant of a WATCHMAN FLXTMdevice.

Open to enrollment. 

Posted By: Dr. Robert Leonardi

Posted Date: 7/29/2021

Location: Heart and Vascular Center

CADFEM

Description
Phase Signal Acquisition (PSAQ) System: Building a Repository of Cardiac Phase Signals for Algorithm Development Recruiting Mostly Female Subjects

Open to enrollment 

Posted By: Dr. Michael Roberts

Posted Date: 4/22/2021

Location: Heart and Vascular Center

PHDEV

Description
Repository of Phase Signals for Pulmonary Hypertension Algorithm Development (PHDEV)

Open to enrollment 

Posted By: Dr. Michael Roberts

Posted Date: 7/8/2020

Location: Heart and Vascular Center

PFO-PAS

Description
Single arm, multi-center study to confirm the safety and effectiveness of the AMPLATZER™ PFO Occluder in the Post-Approval Setting.

Open to enrollment 

Posted By: Dr. Leonardi

Posted Date: 10/13/2017

Location: Heart and Vascular Center